Why do clefts happen?

In many cases we do not yet know. In some case there is a genetic link. This is one of the major areas that we are researching. The gene involved in Van Der Woude syndrome (a cleft-related condition) has already been identified.

Latest

Rona, Richard, Jon and Simon ride 100 miles

Join us in raising funds for the CLEFT: Bridging the Gap! CLEFT has 2 great aims: to support sustainable and multidisciplinary cleft care in lower and middle income countries (surgery is important but only part of the journey), and to support research into the causes and provision of cleft care in the UK.
Zhi's Dublin Marathon Fundraiser

I am raising money to provide long-term, sustainable ways to improve cleft care both in the UK and overseas.
Nick and Kathleen's Wedding Fundraiser

We are raising money to provide long-term, sustainable ways to improve cleft care both in the UK and overseas.
The difference a Comprehensive Cleft and Craniofacial Centre can make

During his visit to Dhaka earlier this year, Mr Brian Sommerlad (Chair of CLEFT and Consultant Plastic Surgeon) saw a number of familiar faces in the clinic. Shahriah and Khadjiatul are two patients requiring a large number of operations and complex treatments throughout their lifetime.

Why do we need research into clefts?

Research enables the discovery of new, better and kinder treatments for clefts.
What is Velopharyngeal Insufficiency?

In the normal palate, the muscles of the soft palate (velum) are responsible for closing the velo-pharyngeal opening (the opening between the palate and the pharynx – the back wall of the throat).
What is a submucous cleft palate?

A submucous cleft palate is a variety of cleft palate where the palate may look relatively unaffected but the muscles that lift the palate for speech are abnormal.
Can clefts have psychological effects?

In 21st century society, where looks seem to be paramount, ‘looking different’ can cause a severe sense of insecurity and inadequacy.
What are the physical effects of cleft lip and palate?

Children born with a cleft may suffer from speech and hearing problems.
How frequently do clefts happen?

We know that in the UK one in 700 babies are born with a cleft.
How do clefts happen?

In the womb, the upper lip develops from three parts and the palate develops in two halves, which then join in the middle. Clefts happen when they fail to join normally.
Are there any other conditions associated with clefts?

There may also be other associated conditions.
What is a cleft?

A cleft is a congenital birth defect.

Sheikh Hasina National Institute of Burns and Plastic Surgery

We are working with Bangladeshi specialists at the new Sheikh Hasina National Institute of Burns and Plastic Surgery to create a sustainable centre to treat children with cleft lip and palate.
Nawrin and the C-Arm

This important piece of equipment was supplied by CLEFT and is used to see moving images of the cleft palate. Nawrin is a 13 year old girl who was experiencing speech difficulties and needed the C-Arm to show the cleft team if further surgery was required.
Our mission

CLEFT was established in 2007 with one aim, to help improve the lives of children born with cleft lip and palate, either by funding research into the likely causes of the condition or by helping support teams in lower and middle income countries.
Donate

You can make a one-off donation today or sign up to giving a regular monthly gift. All donations, small or large, will help us to improve the lives of those born with cleft lip and palate both now and in the future. 100% of your donation today will go towards funding an international or research project thanks to a charitable trust covering all our administrative costs until February 2025.
About us

CLEFT was established in 2007 by cleft surgeon Brian Sommerlad - based at Great Ormond Street Hospital for Children, together with a former patient and a patient's grandmother.
The genetics of cleft lip and palate

Investigations into the genetics of cleft lip and palate to understand more about why cleft lip and palate occurs.
Brian Sommerlad, Consultant Plastic Surgeon and Chair of Trustees

For over 40 years, I have been involved in operating on babies, children and adults who have been born with cleft lip and/or palate.
Our research vision

At CLEFT, our vision is of a future where clefts are preventable. Until we get there, we want to improve the lives of those born with cleft lip and palate.
Trusts and Foundations

Today, 1-in-700 babies in the UK are born with a cleft lip and palate, the most common form of birth defect. The impact on a child’s life as they grow is profound. Typically, they will need at least four operations. They may also require ongoing tests, treatment or therapy. It will affect the way they look but also their speech, hearing and dental development. It can leave deep psychological scars.
MRI Speech Assessment

This important research looked at using MRI to assess whether further surgery could improve speech for people with repaired clefts.