We are very proud of the research that we have funded so far at Great Ormond Street and St Andrews Centre, Chelmsford. Research has been carried out in genetics, speech therapy, orthodontics and surgery. We continue to make headway into understanding why clefts occur including a recent breakthrough in genetics (see the FOXF2 Gene Discovery report). The Research Steering Group met recently to look at which new research projects CLEFT should fund. We will update the website with our research news as it develops further.
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Research that CLEFT funded shows how a pioneering surgical technique results in a very low rate of secondary speech surgery and very good speech outcomes in children aged 5 years of age, with less need for speech therapy. Read more
We are delighted that the website [email protected] is now available. Read more
Early on in his career as plastic surgeon, CLEFT Chairman Mr Brian Sommerlad realised that operating techniques could be improved upon and in 1993, he started to use a microscope for surgery. Read more
A project to better understand the way the muscles of the soft palate work to see if improvements can be made to surgical techniques and reduce the need for further operations and speech therapy. Read more
Investigations into the genetics of cleft lip and palate to understand more about why cleft lip and palate occurs. Read more
CLEFT has funded research into the investigation of a gene called the TBX22 that regulates important development events during normal palate function, in order to find new treatments. Read more
This important research looked at using MRI to assess whether further surgery could improve speech for people with repaired clefts. Read more
The Parent Led Articulation Therapy (P.L.A.T) project has been looking at improving speech outcomes for children by enabling parents to help their children with cleft palate speech difficulties. Read more
A genetic defect has been identified in a family from Egypt with a type of palate abnormality and speech disorder apparently not previously described. The FOXF2 research is one of the many projects currently funded by CLEFT, paid for with money raised by our donors and fundraisers. Read more